Starting date
February 14, 2002
Duration (months)
24
Departments
Diagnostics and Public Health
Managers or local contacts
Fracasso Maria Enrica

Cigarette smoking consitutes the major sorse of exposure to carcinogens in the general population. Thus, its quantitative and objective evaluation is essential, particularly in preventive medicine, since the negative health effects of tobacco smoke are well documented. The particulate phase of main stream smoke contains most of IARC (1986) groups 1, 2A and 2B carcinogens. Polycyclic aromatic hydrocarbons (PAHs) and benzene derive primarily from combustion/pyrolysis of tobacco and from tar levels. Aromatic amines depend on the presence of fertilizers with nitates and heterocyclic aromatic amines chiefly from proteins and sugar content of tobacco smoked.
Now IARC (2002)refers that involuntary smoking involves exposure to the same numerous carcinogens and toxic substances that are present in tobacco smoke poduced by active smoking, which is the principal cause of lung cancer.

Project participants

Marzia Cerpelloni
Technical-administrative staff
Maria Enrica Fracasso
Paola Franceschetti
Luigi Perbellini
Publications
Title Authors Year
Comparative investigations in single cell gel electrophoresis (comet assay) in lymphocytes and in the Ames fluctuation test in urine of workers of a rubber factory Franceschetti P. , Perbellini L., Tieghi S., Soldà S., Fracasso M.E. 2002

Activities

Research facilities