- Autori:
-
Piccirilli, Alessandra; Perilli, Mariagrazia; Piccirilli, Valentina; Segatore, Bernardetta; Amicosante, Gianfranco; Maccacaro, Laura; Bazaj, Alda; Naso, Laura; Cascio, Giuliana Lo; Cornaglia, Giuseppe
- Titolo:
-
Molecular characterization of carbapenem-resistant Klebsiella pneumoniae ST14 and ST512 causing bloodstream infections in ICU and surgery wards of a tertiary university hospital of Verona (northern Italy): co-production of KPC-3, OXA-48, and CTX-M-15 β-lactamases
- Anno:
-
2020
- Tipologia prodotto:
-
Articolo in Rivista
- Tipologia ANVUR:
- Articolo su rivista
- Lingua:
-
Inglese
- Formato:
-
Elettronico
- Referee:
-
No
- Nome rivista:
- Diagnostic Microbiology and Infectious Disease
- ISSN Rivista:
- 0732-8893
- N° Volume:
-
96
- Numero o Fascicolo:
-
3
- Intervallo pagine:
-
114968-114968
- Parole chiave:
-
ENTEROBACTERIACEAE; EPIDEMIOLOGY; MORTALITY
- Breve descrizione dei contenuti:
- Klebsiella pneumoniae strain is an important opportunistic pathogen that causes severe nosocomial infections. In the present study a molecular characterization of carbapenem resistant K. pneumoniae, isolated from blood samples of hospitalized patients of Verona University Hospital, was performed. The simultaneous presence of SHV-1/CTX-M-15/KPC-3 and SHV-1/CTX-M-15/OXA-48 serin-β-lactamases was ascertained in the 89% and 11% of K. pneumoniae ST512 and K. pneumoniae ST14, respectively. Molecular characterization of bla genes showed that blaKPC-3 was found in Tn4401a transposon with the tnpR, tnpA, ISKpn6, and ISKpn7 mobile elements whereas blaCTX-M-15 was detected downstream ISEcp1 genetic element. A class 1 integron with a gene cassette of 780 bp corresponding to aadA2 gene was identified in 33 K. pneumoniae ST512 isolates.
- Id prodotto:
-
111769
- Handle IRIS:
-
11562/1009390
- ultima modifica:
-
30 novembre 2022
- Citazione bibliografica:
-
Piccirilli, Alessandra; Perilli, Mariagrazia; Piccirilli, Valentina; Segatore, Bernardetta; Amicosante, Gianfranco; Maccacaro, Laura; Bazaj, Alda; Naso, Laura; Cascio, Giuliana Lo; Cornaglia, Giuseppe,
Molecular characterization of carbapenem-resistant Klebsiella pneumoniae ST14 and ST512 causing bloodstream infections in ICU and surgery wards of a tertiary university hospital of Verona (northern Italy): co-production of KPC-3, OXA-48, and CTX-M-15 β-lactamases
«Diagnostic Microbiology and Infectious Disease»
, vol.
96
, n.
3
,
2020
,
pp. 114968-114968
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