Cancer-related CD15/FUT4 overexpression decreases benefit to agents targeting EGFR or VEGF acting as a novel RAF-MEK-ERK kinase downstream regulator in metastatic colorectal cancer
Cancer-related CD15/FUT4 overexpression decreases benefit to agents targeting EGFR or VEGF acting as a novel RAF-MEK-ERK kinase downstream regulator in metastatic colorectal cancer
(2015)
Cancer-related CD15/FUT4 overexpression decreases benefit to agents targeting EGFR or VEGF acting as a novel RAF-MEK-ERK kinase downstream regulator in metastatic colorectal cancer
Anno:
2015
Tipologia prodotto:
Articolo in Rivista
Tipologia ANVUR:
Articolo su rivista
Lingua:
Inglese
Formato:
A Stampa
Referee:
Sì
Nome rivista:
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
ISSN Rivista:
1756-9966
N° Volume:
34
Numero o Fascicolo:
1
Intervallo pagine:
108-118
Parole chiave:
ERBB3 or FGFR4; CD15/FUT4; EGFR or VEGF; Metastatic CRC
Breve descrizione dei contenuti:
Cancer-related immune antigens in the tumor microenvironment could represent an obstacle to agents targeting EGFR "cetuximab" or VEGF "bevacizumab" in metastatic colorectal cancer (mCRC) patients.