Pubblicazioni

Autori:

Carbone, C; Piro, G; Gaianigo, Nicola; Ligorio, F; Santoro, R; Merz, V; Simionato, F; Zecchetto, C; Falco, G; Conti, G; Kamga, P. T; Krampera, M; Di Nicolantonio, F; De Franceschi, L; Scarpa, A; Tortora, G; Melisi, D.

Titolo:

Adipocytes sustain pancreatic cancer progression through a non-canonical WNT paracrine network inducing ROR2 nuclear shuttling

Anno:

2018

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Referee:

No

Nome rivista:

International Journal of Obesity

ISSN Rivista:

0307-0565

N° Volume:

42

Numero o Fascicolo:

3

Intervallo pagine:

334-343

Parole chiave:

:BODY-MASS INDEX; STEM-CELLS; OBESITY; RESISTANCE; RISK; MICROENVIRONMENT; ADENOCARCINOMA; METAANALYSIS; EXPRESSION; THERAPY

Breve descrizione dei contenuti:

Solid epidemiological evidences connect obesity with incidence, stage, and survival in pancreatic cancer. However, the underlying mechanistic basis linking adipocytes to pancreatic cancer progression remain largely elusive. We hypothesized that factors secreted by adipocytes could be responsible for epithelial-to-mesenchymal transition (EMT) induction and, in turn, a more aggressive phenotype in models of pancreatic preneoplastic lesions.

Id prodotto:

99459

Handle IRIS:

11562/970435

ultima modifica:

15 novembre 2022

Citazione bibliografica:

Carbone, C; Piro, G; Gaianigo, Nicola; Ligorio, F; Santoro, R; Merz, V; Simionato, F; Zecchetto, C; Falco, G; Conti, G; Kamga, P. T; Krampera, M; Di Nicolantonio, F; De Franceschi, L; Scarpa, A; Tortora, G; Melisi, D., Adipocytes sustain pancreatic cancer progression through a non-canonical WNT paracrine network inducing ROR2 nuclear shuttling «International Journal of Obesity» , vol. 42 , n. 3 , 2018 , pp. 334-343

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo