Pubblicazioni

Autori:

Nocini, Riccardo; Muzio, Lorenzo Lo; Gibellini, Davide; Malerba, Giovanni; Milella, Michele; Chirumbolo, Salvatore; Zerman, Nicoletta

Titolo:

Oral microbiota in oropharyngeal cancers: friend or foe?

Anno:

2022

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Referee:

No

Nome rivista:

FRONTIERS IN ONCOLOGY

ISSN Rivista:

2234-943X

N° Volume:

12

Numero o Fascicolo:

948068

Intervallo pagine:

1-7

Parole chiave:

16sRNA; oral cancer; oral immunity; oral microbiome dysbiosis; oropharyngeal cancer (OPSCC)

Breve descrizione dei contenuti:

Oral microbiome is a complex population of micro-organisms, which by cross-talking with the local immune system, plays a major role in the immune homeostasis of the oral cavity, further contributing in the physiology of the gastro-intestinal microbiota. Understanding their involvement in the onset and pathogenesis of oropharyngeal cancers is paramount, despite very few reports deal with the fundamental role exerted by oral microbiota disorders, such as dysbiosis and impairment in the oral microbiome composition as causative factors in the development of oropharyngeal tumors. Current research, via metabolomic or meta-transcriptomic analyses, is wondering how this complex microbial population regulates the immune homeostasis in oral and pharyngeal mucosa and whether changes in bacterial composition may give insights on the role of oral microbiome in the development of oropharyngeal tumors, so to prevent their occurrence.

Pagina Web:

https://doi.org/10.3389/fonc.2022.948068

Id prodotto:

129869

Handle IRIS:

11562/1076126

ultima modifica:

23 febbraio 2023

Citazione bibliografica:

Nocini, Riccardo; Muzio, Lorenzo Lo; Gibellini, Davide; Malerba, Giovanni; Milella, Michele; Chirumbolo, Salvatore; Zerman, Nicoletta, Oral microbiota in oropharyngeal cancers: friend or foe? «FRONTIERS IN ONCOLOGY» , vol. 12 , n. 948068 , 2022 , pp. 1-7

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo