Pubblicazioni

Autori:

Campa, Daniele; Gentiluomo, Manuel; Stein, Angelika; Aoki, Mateus Nóbrega; Oliverius, Martin; Vodičková, Ludmila; Jamroziak, Krzysztof; Theodoropoulos, George; Pasquali, Claudio; Greenhalf, William; Arcidiacono, Paolo Giorgio; Uzunoglu, Faik; Pezzilli, Raffaele; Luchini, Claudio; Puzzono, Marta; Loos, Martin; Giaccherini, Matteo; Katzke, Verena; Mambrini, Andrea; Kiudeliene, Edita; Federico, Kauffmann Emanuele; Johansen, Julia; Hussein, Tamás; Mohelnikova-Duchonova, Beatrice; van Eijck, Casper H J; Brenner, Hermann; Farinella, Riccardo; Pérez, Juan Sainz; Lovecek, Martin; Büchler, Markus W; Hlavac, Viktor; Izbicki, Jakob R; Hackert, Thilo; Chammas, Roger; Zerbi, Alessandro; Lawlor, Rita; Felici, Alessio; Götz, Mara; Capurso, Gabriele; Ginocchi, Laura; Gazouli, Maria; Kupcinskas, Juozas; Cavestro, Giulia Martina; Vodicka, Pavel; Moz, Stefania; Neoptolemos, John P; Kunovsky, Lumir; Bojesen, Stig E; Carrara, Silvia; Gioffreda, Domenica; Morkunas, Egidijus; Abian, Olga; Bunduc, Stefania; Basso, Daniela; Boggi, Ugo; Wlodarczyk, Barbara; Szentesi, Andrea; Vanella, Giuseppe; Chen, Inna; Bijlsma, Maarten F; Kiudelis, Vytautas; Landi, Stefano; Schöttker, Ben; Corradi, Chiara; Giese, Nathalia; Kaaks, Rudolf; Peduzzi, Giulia; Hegyi, Péter; Morelli, Luca; Furbetta, Niccolò; Soucek, Pavel; Latiano, Anna; Talar-Wojnarowska, Renata; Lindgaard, Sidsel C; Dijk, Frederike; Milanetto, Anna Caterina; Tavano, Francesca; Cervena, Klara; Erőss, Bálint; Testoni, Sabrina G; Verhagen-Oldenampsen, Judith H E; Małecka-Wojciesko, Ewa; Costello, Eithne; Salvia, Roberto; Maiello, Evaristo; Ermini, Stefano; Sperti, Cosimo; Holleczek, Bernd; Perri, Francesco; Skieceviciene, Jurgita; Archibugi, Livia; Lucchesi, Maurizio; Rizzato, Cosmeri; Canzian, Federico

Titolo:

The PANcreatic Disease ReseArch (PANDoRA) consortium: ten years' experience of association studies to understand the genetic architecture of pancreatic cancer

Anno:

2023

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Formato:

Elettronico

Referee:

No

Nome rivista:

Critical Review in Oncology/Hematology

ISSN Rivista:

1040-8428

N° Volume:

186

Intervallo pagine:

1-13

Parole chiave:

Pancreatic cancer; chronic pancreatitis; consortium; genetic epidemiology; intraductal papillary mucinous neoplasms; pancreatic ductal adenocarcinoma; pancreatic neuroendocrine tumors

Breve descrizione dei contenuti:

: Pancreatic cancer has an incidence that almost matches its mortality. Only a small number of risk factors and 33 susceptibility loci have been identified. so Moreover, the relative rarity of pancreatic cancer poses significant hurdles for research aimed at increasing our knowledge of the genetic mechanisms contributing to the disease. Additionally, the inability to adequately power research questions prevents small monocentric studies from being successful. Several consortia have been established to pursue a better understanding of the genetic architecture of pancreatic cancers. The Pancreatic disease research (PANDoRA) consortium is the largest in Europe. PANDoRA is spread across 12 European countries, Brazil and Japan, bringing together 29 basic and clinical research groups. In the last ten years, PANDoRA has contributed to the discovery of 25 susceptibility loci, a feat that will be instrumental in stratifying the population by risk and optimizing preventive strategies.

Id prodotto:

133734

Handle IRIS:

11562/1093628

ultima modifica:

15 settembre 2023

Citazione bibliografica:

Campa, Daniele; Gentiluomo, Manuel; Stein, Angelika; Aoki, Mateus Nóbrega; Oliverius, Martin; Vodičková, Ludmila; Jamroziak, Krzysztof; Theodoropoulos, George; Pasquali, Claudio; Greenhalf, William; Arcidiacono, Paolo Giorgio; Uzunoglu, Faik; Pezzilli, Raffaele; Luchini, Claudio; Puzzono, Marta; Loos, Martin; Giaccherini, Matteo; Katzke, Verena; Mambrini, Andrea; Kiudeliene, Edita; Federico, Kauffmann Emanuele; Johansen, Julia; Hussein, Tamás; Mohelnikova-Duchonova, Beatrice; van Eijck, Casper H J; Brenner, Hermann; Farinella, Riccardo; Pérez, Juan Sainz; Lovecek, Martin; Büchler, Markus W; Hlavac, Viktor; Izbicki, Jakob R; Hackert, Thilo; Chammas, Roger; Zerbi, Alessandro; Lawlor, Rita; Felici, Alessio; Götz, Mara; Capurso, Gabriele; Ginocchi, Laura; Gazouli, Maria; Kupcinskas, Juozas; Cavestro, Giulia Martina; Vodicka, Pavel; Moz, Stefania; Neoptolemos, John P; Kunovsky, Lumir; Bojesen, Stig E; Carrara, Silvia; Gioffreda, Domenica; Morkunas, Egidijus; Abian, Olga; Bunduc, Stefania; Basso, Daniela; Boggi, Ugo; Wlodarczyk, Barbara; Szentesi, Andrea; Vanella, Giuseppe; Chen, Inna; Bijlsma, Maarten F; Kiudelis, Vytautas; Landi, Stefano; Schöttker, Ben; Corradi, Chiara; Giese, Nathalia; Kaaks, Rudolf; Peduzzi, Giulia; Hegyi, Péter; Morelli, Luca; Furbetta, Niccolò; Soucek, Pavel; Latiano, Anna; Talar-Wojnarowska, Renata; Lindgaard, Sidsel C; Dijk, Frederike; Milanetto, Anna Caterina; Tavano, Francesca; Cervena, Klara; Erőss, Bálint; Testoni, Sabrina G; Verhagen-Oldenampsen, Judith H E; Małecka-Wojciesko, Ewa; Costello, Eithne; Salvia, Roberto; Maiello, Evaristo; Ermini, Stefano; Sperti, Cosimo; Holleczek, Bernd; Perri, Francesco; Skieceviciene, Jurgita; Archibugi, Livia; Lucchesi, Maurizio; Rizzato, Cosmeri; Canzian, Federico, The PANcreatic Disease ReseArch (PANDoRA) consortium: ten years' experience of association studies to understand the genetic architecture of pancreatic cancer «Critical Review in Oncology/Hematology» , vol. 186 , 2023 , pp. 1-13

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