Pubblicazioni

Autori:

Lamberti, Monica; Uccello, Rossella; Monaco, MARIA GRAZIA LOURDES; Muoio, Mariarosaria; Feola, Daniela; Sannolo, Nicola; Nienhaus, Albert; Chiodini, Paolo

Titolo:

Tuberculin Skin Test and Quantiferon test agreement and influencing factors in tuberculosis screening of healthcare workers: A systematic review and meta-analysis

Anno:

2015

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Formato:

Elettronico

Referee:

Sì

Nome rivista:

JOURNAL OF OCCUPATIONAL MEDICINE AND TOXICOLOGY

ISSN Rivista:

1745-6673

N° Volume:

10

Numero o Fascicolo:

1

Editore:

London : Biomed Central

Intervallo pagine:

1-13

Parole chiave:

Cohen's κ; Health surveillance; Healthcare workers; Meta-analysis; Quantiferon TB Gold; Tuberculin Skin Test; Tuberculosis

Breve descrizione dei contenuti:

Objective: A systematic review and meta-analysis was conducted to evaluate the agreement between Tuberculin Skin Test (TST) and Quantiferon (QFT) in screening for tuberculosis (TB) infection among healthcare workers (HCWs) and to estimate associations between TST and QFT agreement and variables of interest, such as Bacillus Calmette-Guérin (BCG) vaccination and incidence of TB. Methods: Cross-sectional and longitudinal studies on HCWs, published in English until October 2013, comparing TST and QFT results, were selected. For each study Cohen’s κ value and a 95% confidence interval were calculated. Summary measures and indexes of heterogeneity between studies were calculated. Results: 29 studies were selected comprising a total of 11,434 HCWs. Cohen’s κ for agreement between TST and QFT for 24 of them was 0.28 (95% CI 0.22 to 0.35), with the best value in high TB incidence countries and the lowest rate of BCG vaccination. Conclusion: Currently, there is no gold standard for TB screening and the most-used diagnostic tools show low agreement. For evidence-based health surveillance in HCWs, occupational physicians need to consider a nu

Id prodotto:

141532

Handle IRIS:

11562/1141048

ultima modifica:

10 ottobre 2024

Citazione bibliografica:

Lamberti, Monica; Uccello, Rossella; Monaco, MARIA GRAZIA LOURDES; Muoio, Mariarosaria; Feola, Daniela; Sannolo, Nicola; Nienhaus, Albert; Chiodini, Paolo, Tuberculin Skin Test and Quantiferon test agreement and influencing factors in tuberculosis screening of healthcare workers: A systematic review and meta-analysis «JOURNAL OF OCCUPATIONAL MEDICINE AND TOXICOLOGY» , vol. 10 , n. 1 , 2015 , pp. 1-13

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo