Pubblicazioni

Autori:

Matrone, Fabio; Urso, Luca; Girometti, Rossano; Polesel, Jerry; Sepulcri, Matteo; Pierantoni, Francesco; Artioli, Paolo; Caliò, Anna; Campo, Irene; Cimadamore, Alessia; Munari, Enrico; Ongaro, Luca; Orlando, Valentina; Sachs, Camilla; Veccia, Alessandro; Antonelli, Alessandro; Bortolus, Roberto; Brunelli, Matteo; Caffo, Orazio; Evangelista, Laura; Salgarello, Matteo; Basso, Umberto; De Vivo, Rocco; Gardi, Mario; Guttilla, Andrea; Andrea Signor, Marco; Zattoni, Fabio; Alongi, Filippo; Montesi, Giampaolo; Giannarini, Gianluca

Titolo:

The expanding role of next-generation imaging in prostate cancer management: a cross-sectional survey exploring the clinical practice of uro-oncologists in North-Eastern Italy; on behalf of GUONE (Gruppo Uro-Oncologico del Nord-Est)

Anno:

2025

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Formato:

Elettronico

Referee:

No

Nome rivista:

THERAPEUTIC ADVANCES IN UROLOGY

ISSN Rivista:

1756-2872

N° Volume:

17

Intervallo pagine:

1-13

Parole chiave:

PET/MRI; PSMA PET/CT; mpMRI; prostate cancer; whole-body MRI

Breve descrizione dei contenuti:

Background: Next-generation imaging (NGI) technologies such as multiparametric magnetic resonance imaging (mpMRI) and total-body NGI (tbNGI) methodologies including choline, fluciclovine or PSMA positron emission tomography/computed tomography (PET/CT), whole-body MRI (wbMRI), and PET/MRI are becoming increasingly available, but their use in different prostate cancer (PCa) settings is under debate. The Gruppo Uro-Oncologico del Nord-Est (GUONE) designed a survey to explore the current clinical practice of NGI utilization in a specific macro-region in North-Eastern Italy. Methods: A cross-sectional survey was conducted by administering an anonymous online multiple-choice questionnaire to uro-oncologists practicing in North-Eastern Italy, using the Google Forms® platform. The use of NGI was investigated in the following settings: primary staging of PCa; management of biochemical (BCR) and local recurrence (LR); re-staging in metastatic hormone-sensitive PCa (mHSPC), metastatic castration-resistant PCa (mCRPC), non-metastatic CRPC (nmCRPC), and oligometastatic PCa (OMPC). Results: In all, 100 uro-oncologists accessed and completed the survey. In primary N/M staging, the use of tbNGI increases in accordance with NCCN risk groups. Re-staging with choline and PSMA PET/CT is the prevalent choice in the case of BCR after radical prostatectomy. Moreover, when the PSA value rises, there is a parallel increased use of tbNGI. When an LR is suspected, PSMA PET/CT plus mpMRI is the most selected option. Re-staging with tbNGI (PSMA PET/CT) is preferred in mHSPC, mCRPC, and nmCRPC patients in case of progression of disease. Overall, there is a limited use of wbMRI and PET/MRI in all the settings investigated. Conclusion: Our survey describes the expanding role of NGI modalities in the management of PCa patients, from primary staging and re-staging to management of advanced PCa and assessment of treatment response. Several controversial issues have emerged, which need to be addressed in prospective studies to develop a standardized and cost-effective NGI utilization.

Id prodotto:

144732

Handle IRIS:

11562/1157629

ultima modifica:

6 aprile 2025

Citazione bibliografica:

Matrone, Fabio; Urso, Luca; Girometti, Rossano; Polesel, Jerry; Sepulcri, Matteo; Pierantoni, Francesco; Artioli, Paolo; Caliò, Anna; Campo, Irene; Cimadamore, Alessia; Munari, Enrico; Ongaro, Luca; Orlando, Valentina; Sachs, Camilla; Veccia, Alessandro; Antonelli, Alessandro; Bortolus, Roberto; Brunelli, Matteo; Caffo, Orazio; Evangelista, Laura; Salgarello, Matteo; Basso, Umberto; De Vivo, Rocco; Gardi, Mario; Guttilla, Andrea; Andrea Signor, Marco; Zattoni, Fabio; Alongi, Filippo; Montesi, Giampaolo; Giannarini, Gianluca, The expanding role of next-generation imaging in prostate cancer management: a cross-sectional survey exploring the clinical practice of uro-oncologists in North-Eastern Italy; on behalf of GUONE (Gruppo Uro-Oncologico del Nord-Est) «THERAPEUTIC ADVANCES IN UROLOGY» , vol. 17 , 2025 , pp. 1-13

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