Publications

Authors:

Piccirilli, Alessandra; Perilli, Mariagrazia; Piccirilli, Valentina; Segatore, Bernardetta; Amicosante, Gianfranco; Maccacaro, Laura; Bazaj, Alda; Naso, Laura; Cascio, Giuliana Lo; Cornaglia, Giuseppe

Title:

Molecular characterization of carbapenem-resistant Klebsiella pneumoniae ST14 and ST512 causing bloodstream infections in ICU and surgery wards of a tertiary university hospital of Verona (northern Italy): co-production of KPC-3, OXA-48, and CTX-M-15 β-lactamases

Year:

2020

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

Elettronico

Referee:

No

Name of journal:

Diagnostic Microbiology and Infectious Disease

ISSN of journal:

0732-8893

N° Volume:

96

Number or Folder:

3

Page numbers:

114968-114968

Keyword:

ENTEROBACTERIACEAE; EPIDEMIOLOGY; MORTALITY

Short description of contents:

Klebsiella pneumoniae strain is an important opportunistic pathogen that causes severe nosocomial infections. In the present study a molecular characterization of carbapenem resistant K. pneumoniae, isolated from blood samples of hospitalized patients of Verona University Hospital, was performed. The simultaneous presence of SHV-1/CTX-M-15/KPC-3 and SHV-1/CTX-M-15/OXA-48 serin-β-lactamases was ascertained in the 89% and 11% of K. pneumoniae ST512 and K. pneumoniae ST14, respectively. Molecular characterization of bla genes showed that blaKPC-3 was found in Tn4401a transposon with the tnpR, tnpA, ISKpn6, and ISKpn7 mobile elements whereas blaCTX-M-15 was detected downstream ISEcp1 genetic element. A class 1 integron with a gene cassette of 780 bp corresponding to aadA2 gene was identified in 33 K. pneumoniae ST512 isolates.

Product ID:

111769

Handle IRIS:

11562/1009390

Last Modified:

November 30, 2022

Bibliographic citation:

Piccirilli, Alessandra; Perilli, Mariagrazia; Piccirilli, Valentina; Segatore, Bernardetta; Amicosante, Gianfranco; Maccacaro, Laura; Bazaj, Alda; Naso, Laura; Cascio, Giuliana Lo; Cornaglia, Giuseppe, Molecular characterization of carbapenem-resistant Klebsiella pneumoniae ST14 and ST512 causing bloodstream infections in ICU and surgery wards of a tertiary university hospital of Verona (northern Italy): co-production of KPC-3, OXA-48, and CTX-M-15 β-lactamases «Diagnostic Microbiology and Infectious Disease» , vol. 96 , n. 3 , 2020 , pp. 114968-114968

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo