Targeted next-generation sequencing identifies genomic abnormalities potentially driving the prognosis of early-stage invasive lobular breast carcinoma patients stratified according to a validated clinico-pathological model
Targeted next-generation sequencing identifies genomic abnormalities potentially driving the prognosis of early-stage invasive lobular breast carcinoma patients stratified according to a validated clinico-pathological model
(2020)
Targeted next-generation sequencing identifies genomic abnormalities potentially driving the prognosis of early-stage invasive lobular breast carcinoma patients stratified according to a validated clinico-pathological model
Year:
2020
Type of item:
Articolo in Rivista
Tipologia ANVUR:
Articolo su rivista
Language:
Inglese
Referee:
No
Name of journal:
THE BREAST
ISSN of journal:
0960-9776
N° Volume:
50
Page numbers:
56-63
Keyword:
Breast cancer; CDK4; Lobular; Next-generation sequencing; Prognosis; Transcriptome analysis
Short description of contents:
The clinico-pathological and molecular factors that drive the prognosis of invasive lobular breast carcinoma (ILC) are not entirely explored. In this regard, the development and validation of a prognostic model for ILC and the investigation of the distribution of molecular abnormalities (focusing on CDK4/6 alterations) according to prognosis were the aims of this study.
Product ID:
112396
Handle IRIS:
11562/1010760
Last Modified:
November 16, 2022
Bibliographic citation:
Carbognin, Luisa; Simbolo, Michele; Caliò, Anna; Vicentini, Caterina; Delfino, Pietro; Sperduti, Isabella; Fassan, Matteo; Schettini, Francesco; Dieci, Maria Vittoria; Griguolo, Gaia; Pilotto, Sara; Fiorio, Elena; Arpino, Grazia; Guarneri, Valentina; De Placido, Sabino; Conte, Pierfranco; Manfrin, Erminia; Brunelli, Matteo; Scambia, Giovanni; Scarpa, Aldo; Tortora, Giampaolo; Bria, Emilio,
Targeted next-generation sequencing identifies genomic abnormalities potentially driving the prognosis of early-stage invasive lobular breast carcinoma patients stratified according to a validated clinico-pathological model«THE BREAST»
, vol. 50
, 2020
, pp. 56-63