Publications

Authors:

Agodi, A; Barchitta, M; Auxilia, F; Brusaferro, S; D'Errico, M M; Montagna, M T; Pasquarella, C; Tardivo, S; Arrigoni, C; Fabiani, L; Laurenti, P; Mattaliano, A R; Orsi, G B; Squeri, R; Torregrossa, M V; Mura, I

Title:

Epidemiology of intensive care unit-acquired sepsis in Italy: results of the SPIN-UTI network

Year:

2018

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

A Stampa

Referee:

No

Name of journal:

Annali di Igiene

ISSN of journal:

1120-9135

N° Volume:

30

Number or Folder:

5 Supple 2

Page numbers:

15-21

Keyword:

Healthcare-associated infections; Mortality; Sepsis; Surveillance; Aged; Cross Infection; Female; Hospital Mortality; Humans; Incidence; Intensive Care Units; Italy; Length of Stay; Male; Middle Aged; Population Surveillance; Prospective Studies; Sepsis; Shock, Septic; Time Factors

Short description of contents:

Background. Sepsis is the major cause of mortality from any infectious disease worldwide. Sepsis may be the result of a healthcare associated infection (HAI): the most frequent adverse events during care delivery especially in Intensive Care Units (ICUs). The main aim of the present study was to describe the epidemiology of ICU-acquired sepsis and related outcomes among patients enrolled in the framework of the Italian Nosocornial Infections Surveillance in ICUs - SPIN-UTI project.Study design. Prospective multicenter study.Methods. The SPIN-UTI network adopted the European protocols for patient-based HAI surveillance.Results. During the five editions of the SPIN-UTI project, from 2008 to 2017, 47.0% of HAIs has led to sepsis in 832 patients. Overall, 57.0% episodes were classified as sepsis, 20.5% as severe sepsis and 22.5% as septic shock. The most common isolated microorganisms from sepsis episodes were Acinetobacter baumannii, Klebsiella pneumoniae and Pseudomonas aeruginosa The rase fatality rate increased with the severity of sepsis and the mean length of ICU-stay was significantly higher in patients with ICU-acquired sepsis than in patients without.Conclusions. Our study provides evidence that ICU-acquired sepsis occurs frequently in Italian ICU patients and is associated with a high case fatality rate and increased length of stay. However, in order to explain these findings further analyses are needed in this population of ICU patients.

Product ID:

117490

Handle IRIS:

11562/1029617

Last Modified:

November 15, 2022

Bibliographic citation:

Agodi, A; Barchitta, M; Auxilia, F; Brusaferro, S; D'Errico, M M; Montagna, M T; Pasquarella, C; Tardivo, S; Arrigoni, C; Fabiani, L; Laurenti, P; Mattaliano, A R; Orsi, G B; Squeri, R; Torregrossa, M V; Mura, I, Epidemiology of intensive care unit-acquired sepsis in Italy: results of the SPIN-UTI network «Annali di Igiene» , vol. 30 , n. 5 Supple 2 , 2018 , pp. 15-21

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