Publications

Authors:

Pardo, Alessia; Signoriello, Annarita; Signoretto, Caterina; Messina, Elena; Carelli, Maria; Tessari, Maddalena; De Manna, Nunzio Davide; Rossetti, Cecilia; Albanese, Massimo; Lombardo, Giorgio; Luciani, Giovanni Battista

Title:

Detection of Periodontal Pathogens in Oral Samples and Cardiac Specimens in Patients Undergoing Aortic Valve Replacement: A Pilot Study

Year:

2021

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

Elettronico

Referee:

No

Name of journal:

JOURNAL OF CLINICAL MEDICINE

ISSN of journal:

2077-0383

N° Volume:

10

Number or Folder:

17

Page numbers:

1-13

Keyword:

bacteria; cardiovascular; dental plaque; periodontitis; valve

Short description of contents:

This observational study aimed to: (i) assess the presence of periodontal disease among patients requiring aortic valve replacement; (ii) investigate the presence of oral pathogens in aortic valve specimens and compare them with the microorganisms detected in the oral cavity. Twenty-six patients (15 men and 11 women) were scheduled to be visited the day before the cardiac surgery: periodontal conditions were accurately registered through clinical and radiographic examinations; dental plaque or salivary samples were collected. Valve specimens were collected during surgical aortic valve replacement and analyzed for pathogens detection through microbiological 16SrRna gene sequencing. Bacteria found in plaque samples and valve specimens were assessed according to oral and periodontal conditions. A qualitative comparison between oral and cardiac profiles of the microorganisms detected was performed. The overall number of patients examined for soft tissues conditions was 19, as 7 patients were edentulous. Twelve and three individuals, respectively, presented moderate and severe periodontitis. Nine valves were found to be positive for the presence of oral and periodontopathic bacterial DNA. The microbial species found in valve samples of patients with periodontitis suggest that the presence of these microorganisms in valvular tissue seems to be not coincidental.

Product ID:

122424

Handle IRIS:

11562/1048791

Last Modified:

January 29, 2025

Bibliographic citation:

Pardo, Alessia; Signoriello, Annarita; Signoretto, Caterina; Messina, Elena; Carelli, Maria; Tessari, Maddalena; De Manna, Nunzio Davide; Rossetti, Cecilia; Albanese, Massimo; Lombardo, Giorgio; Luciani, Giovanni Battista, Detection of Periodontal Pathogens in Oral Samples and Cardiac Specimens in Patients Undergoing Aortic Valve Replacement: A Pilot Study «JOURNAL OF CLINICAL MEDICINE» , vol. 10 , n. 17 , 2021 , pp. 1-13

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo