Publications

Authors:

Campa, Daniele; Gentiluomo, Manuel; Stein, Angelika; Aoki, Mateus Nóbrega; Oliverius, Martin; Vodičková, Ludmila; Jamroziak, Krzysztof; Theodoropoulos, George; Pasquali, Claudio; Greenhalf, William; Arcidiacono, Paolo Giorgio; Uzunoglu, Faik; Pezzilli, Raffaele; Luchini, Claudio; Puzzono, Marta; Loos, Martin; Giaccherini, Matteo; Katzke, Verena; Mambrini, Andrea; Kiudeliene, Edita; Federico, Kauffmann Emanuele; Johansen, Julia; Hussein, Tamás; Mohelnikova-Duchonova, Beatrice; van Eijck, Casper H J; Brenner, Hermann; Farinella, Riccardo; Pérez, Juan Sainz; Lovecek, Martin; Büchler, Markus W; Hlavac, Viktor; Izbicki, Jakob R; Hackert, Thilo; Chammas, Roger; Zerbi, Alessandro; Lawlor, Rita; Felici, Alessio; Götz, Mara; Capurso, Gabriele; Ginocchi, Laura; Gazouli, Maria; Kupcinskas, Juozas; Cavestro, Giulia Martina; Vodicka, Pavel; Moz, Stefania; Neoptolemos, John P; Kunovsky, Lumir; Bojesen, Stig E; Carrara, Silvia; Gioffreda, Domenica; Morkunas, Egidijus; Abian, Olga; Bunduc, Stefania; Basso, Daniela; Boggi, Ugo; Wlodarczyk, Barbara; Szentesi, Andrea; Vanella, Giuseppe; Chen, Inna; Bijlsma, Maarten F; Kiudelis, Vytautas; Landi, Stefano; Schöttker, Ben; Corradi, Chiara; Giese, Nathalia; Kaaks, Rudolf; Peduzzi, Giulia; Hegyi, Péter; Morelli, Luca; Furbetta, Niccolò; Soucek, Pavel; Latiano, Anna; Talar-Wojnarowska, Renata; Lindgaard, Sidsel C; Dijk, Frederike; Milanetto, Anna Caterina; Tavano, Francesca; Cervena, Klara; Erőss, Bálint; Testoni, Sabrina G; Verhagen-Oldenampsen, Judith H E; Małecka-Wojciesko, Ewa; Costello, Eithne; Salvia, Roberto; Maiello, Evaristo; Ermini, Stefano; Sperti, Cosimo; Holleczek, Bernd; Perri, Francesco; Skieceviciene, Jurgita; Archibugi, Livia; Lucchesi, Maurizio; Rizzato, Cosmeri; Canzian, Federico

Title:

The PANcreatic Disease ReseArch (PANDoRA) consortium: ten years' experience of association studies to understand the genetic architecture of pancreatic cancer

Year:

2023

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

Elettronico

Referee:

No

Name of journal:

Critical Review in Oncology/Hematology

ISSN of journal:

1040-8428

N° Volume:

186

Page numbers:

1-13

Keyword:

Pancreatic cancer; chronic pancreatitis; consortium; genetic epidemiology; intraductal papillary mucinous neoplasms; pancreatic ductal adenocarcinoma; pancreatic neuroendocrine tumors

Short description of contents:

: Pancreatic cancer has an incidence that almost matches its mortality. Only a small number of risk factors and 33 susceptibility loci have been identified. so Moreover, the relative rarity of pancreatic cancer poses significant hurdles for research aimed at increasing our knowledge of the genetic mechanisms contributing to the disease. Additionally, the inability to adequately power research questions prevents small monocentric studies from being successful. Several consortia have been established to pursue a better understanding of the genetic architecture of pancreatic cancers. The Pancreatic disease research (PANDoRA) consortium is the largest in Europe. PANDoRA is spread across 12 European countries, Brazil and Japan, bringing together 29 basic and clinical research groups. In the last ten years, PANDoRA has contributed to the discovery of 25 susceptibility loci, a feat that will be instrumental in stratifying the population by risk and optimizing preventive strategies.

Product ID:

133734

Handle IRIS:

11562/1093628

Last Modified:

September 15, 2023

Bibliographic citation:

Campa, Daniele; Gentiluomo, Manuel; Stein, Angelika; Aoki, Mateus Nóbrega; Oliverius, Martin; Vodičková, Ludmila; Jamroziak, Krzysztof; Theodoropoulos, George; Pasquali, Claudio; Greenhalf, William; Arcidiacono, Paolo Giorgio; Uzunoglu, Faik; Pezzilli, Raffaele; Luchini, Claudio; Puzzono, Marta; Loos, Martin; Giaccherini, Matteo; Katzke, Verena; Mambrini, Andrea; Kiudeliene, Edita; Federico, Kauffmann Emanuele; Johansen, Julia; Hussein, Tamás; Mohelnikova-Duchonova, Beatrice; van Eijck, Casper H J; Brenner, Hermann; Farinella, Riccardo; Pérez, Juan Sainz; Lovecek, Martin; Büchler, Markus W; Hlavac, Viktor; Izbicki, Jakob R; Hackert, Thilo; Chammas, Roger; Zerbi, Alessandro; Lawlor, Rita; Felici, Alessio; Götz, Mara; Capurso, Gabriele; Ginocchi, Laura; Gazouli, Maria; Kupcinskas, Juozas; Cavestro, Giulia Martina; Vodicka, Pavel; Moz, Stefania; Neoptolemos, John P; Kunovsky, Lumir; Bojesen, Stig E; Carrara, Silvia; Gioffreda, Domenica; Morkunas, Egidijus; Abian, Olga; Bunduc, Stefania; Basso, Daniela; Boggi, Ugo; Wlodarczyk, Barbara; Szentesi, Andrea; Vanella, Giuseppe; Chen, Inna; Bijlsma, Maarten F; Kiudelis, Vytautas; Landi, Stefano; Schöttker, Ben; Corradi, Chiara; Giese, Nathalia; Kaaks, Rudolf; Peduzzi, Giulia; Hegyi, Péter; Morelli, Luca; Furbetta, Niccolò; Soucek, Pavel; Latiano, Anna; Talar-Wojnarowska, Renata; Lindgaard, Sidsel C; Dijk, Frederike; Milanetto, Anna Caterina; Tavano, Francesca; Cervena, Klara; Erőss, Bálint; Testoni, Sabrina G; Verhagen-Oldenampsen, Judith H E; Małecka-Wojciesko, Ewa; Costello, Eithne; Salvia, Roberto; Maiello, Evaristo; Ermini, Stefano; Sperti, Cosimo; Holleczek, Bernd; Perri, Francesco; Skieceviciene, Jurgita; Archibugi, Livia; Lucchesi, Maurizio; Rizzato, Cosmeri; Canzian, Federico, The PANcreatic Disease ReseArch (PANDoRA) consortium: ten years' experience of association studies to understand the genetic architecture of pancreatic cancer «Critical Review in Oncology/Hematology» , vol. 186 , 2023 , pp. 1-13

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo