Publications

Authors:

Corianò, Matilde; Lazzarin, Alessandro; Maffezzoli, Michele; Santoni, Matteo; Mazzaschi, Giulia; Rodella, Sara; Simoni, Nicola; Lai, Eleonora; Maruzzo, Marco; Basso, Umberto; Bimbatti, Davide; Iacovelli, Roberto; Anghelone, Annunziato; Fiala, Ondřej; Rebuzzi, Sara Elena; Fornarini, Giuseppe; Lolli, Cristian; Massari, Francesco; Rosellini, Matteo; Mollica, Veronica; Nasso, Cecilia; Acunzo, Alessandro; Silini, Enrico Maria; Quaini, Federico; De Filippo, Massimo; Brunelli, Matteo; Banna, Giuseppe L; Rescigno, Pasquale; Signori, Alessio; Buti, Sebastiano

Title:

Role of Hb to RDW ratio in metastatic renal cell carcinoma patients treated with first-line immunotherapy combinations

Year:

2025

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Referee:

No

Name of journal:

IMMUNOTHERAPY

ISSN of journal:

1750-743X

N° Volume:

17

Number or Folder:

1

Page numbers:

25-35

Keyword:

NLR; Prognostic score; RDW; hemoglobin; immune checkpoint inhibitors; metastatic renal cell carcinoma; ratio; tyrosine-kinase inhibitors

Short description of contents:

Background: The present study aimed to investigate the prognostic and predictive roles of Hb/RDW ratio in patients with mRCC treated with first-line immunotherapy combinations (TKI plus ICI or ICI plus ICI). Materials and methods: We performed a sub-analysis of a multicenter retrospective observational study (ARON-1 project) involving patients with mRCC treated with first-line immunotherapy combinations. Results: Three hundred and twenty-nine patients were enrolled, 244 males and 85 females. Median age was 65.5 years. The prognostic impact of the Hb/RDW ratio on PFS and OS was observed in the whole population examined. Hb/RDW ratio had a correlation with neutrophil-to-lymphocyte ratio (NLR), a blood inflammatory parameter. Conclusion: Hb/RDW ratio is a new inflammatory prognostic factor, easy to use in daily clinical practice.

Note:

Epub 2025 Jan 20

Product ID:

143947

Handle IRIS:

11562/1151107

Last Modified:

April 4, 2025

Bibliographic citation:

Corianò, Matilde; Lazzarin, Alessandro; Maffezzoli, Michele; Santoni, Matteo; Mazzaschi, Giulia; Rodella, Sara; Simoni, Nicola; Lai, Eleonora; Maruzzo, Marco; Basso, Umberto; Bimbatti, Davide; Iacovelli, Roberto; Anghelone, Annunziato; Fiala, Ondřej; Rebuzzi, Sara Elena; Fornarini, Giuseppe; Lolli, Cristian; Massari, Francesco; Rosellini, Matteo; Mollica, Veronica; Nasso, Cecilia; Acunzo, Alessandro; Silini, Enrico Maria; Quaini, Federico; De Filippo, Massimo; Brunelli, Matteo; Banna, Giuseppe L; Rescigno, Pasquale; Signori, Alessio; Buti, Sebastiano, Role of Hb to RDW ratio in metastatic renal cell carcinoma patients treated with first-line immunotherapy combinations «IMMUNOTHERAPY» , vol. 17 , n. 1 , 2025 , pp. 25-35

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