Publications

Authors:

Perbellini, Luigi; Princivalle, Andrea; Cerpelloni, Marzia; Caprini, Alessia

Title:

Biological monitoring of occupational exposure to acrylonitrile

Year:

2003

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Italiano

Referee:

No

Name of journal:

GIORNALE ITALIANO DI MEDICINA DEL LAVORO ED ERGONOMIA

ISSN of journal:

1592-7830

N° Volume:

25 Suppl(3):

:

PI-ME Tipografia Editrice:via Vigentina 136, I 27100 Pavia Italy:011 39 0382 572169, EMAIL: marcello.imbriani@fsm.it, Fax: 011 39 0382 572102

Page numbers:

41-42

Keyword:

Acrylonitrile; biological monitoring; occupational exposure

Short description of contents:

Acrylonitrile (ACN) is a solvent widely used in industry especially as raw material in the manufacturing of acrylic fibres, clothes and domestic furniture. It is also used in manufacturing of resins (ACN-butadiene-styrene...) and for production of nitrilic elastomers. Some researchers proposed the biological monitoring of occupational exposure to ACN by measuring the solvent in the urine, but results were widely spread especially in relation to the analytical method used. This article reports the main aspects that can reduce the variability of results. We checked several ACN solutions in water and urine after heating at 90 degrees C for 1, 3, 5, 8 and 16 hours. Water solutions maintained their ACN concentration in all the checked conditions, while urine concentrations of ACN in urine deceased during the conditioning time until 80% of their initial concentration. The analysis of ACN in urine provided by workers potentially exposed to ACN and by control subjects gave median results of 1.9 and 2.0 micrograms/g creat, without any statistical difference. The results split in relation to the smoking habit showed a statistic difference: the median values of ACN were 1.7 and 4.7 micrograms/g creat, respectively among the 175 non-smokers and 57 smokers.

Product ID:

87597

Handle IRIS:

11562/233312

Deposited On:

April 24, 2012

Last Modified:

November 14, 2022

Bibliographic citation:

Perbellini, Luigi; Princivalle, Andrea; Cerpelloni, Marzia; Caprini, Alessia, Biological monitoring of occupational exposure to acrylonitrile «GIORNALE ITALIANO DI MEDICINA DEL LAVORO ED ERGONOMIA» , vol. 25 Suppl(3): , 2003 , pp. 41-42

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