Publications

Authors:

Mazzariol, Annarita; LO CASCIO, Giuliana; Kocsis, Erika; Maccacaro, L; Fontana, Roberta; Cornaglia, Giuseppe

Title:

Outbreak of linezolid-resistant Staphylococcus haemolyticus in an Italian intensive care unit

Year:

2012

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Referee:

No

Name of journal:

European Journal of Clinical Microbiology and Infectious Diseases

ISSN of journal:

0934-9723

N° Volume:

31

Number or Folder:

4

Page numbers:

523-527

Keyword:

linezolid-resistant; Staphylococcus haemolyticus; Intensive Care Unit

Short description of contents:

We report an outbreak of linezolid-resistant Staphylococcus haemolyticus strains (MIC 32 mg/L) in patients admitted to the Verona University Hospital Intensive Care Unit. The strains proved to be clonally related at pulsed field gel electrophoresis. All the strains showed the G2576T mutation responsible for linezolid-resistance and retained their resistance even after several passages on antibiotic-free medium. After a decade of linezolid use, multifocal emergence of linezolid resistance in coagulase-negative staphylococci has become an important matter of concern and mandates stricter control over the use of this antibiotic in order to preserve its clinical utility.

Product ID:

61272

Handle IRIS:

11562/359811

Deposited On:

March 30, 2012

Last Modified:

November 11, 2022

Bibliographic citation:

Mazzariol, Annarita; LO CASCIO, Giuliana; Kocsis, Erika; Maccacaro, L; Fontana, Roberta; Cornaglia, Giuseppe, Outbreak of linezolid-resistant Staphylococcus haemolyticus in an Italian intensive care unit «European Journal of Clinical Microbiology and Infectious Diseases» , vol. 31 , n. 4 , 2012 , pp. 523-527

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