Publications

Authors:

Baiocchi, Gl; Marrelli, D; Verlato, Giuseppe; Morgagni, P; Giacopuzzi, Simone; Coniglio, A; Marchet, A; Rosa, F; Giulii Capponi, M; Di Leo, A; Saragoni, L; Ansaloni, L; Pacelli, F; Nitti, D; D’Ugo, D; Roviello, F; Tiberio, G; Giulini, Sm; DE MANZONI, Giovanni

Title:

Follow-up after gastrectomy for cancer. An appraisal of the Italian Research Group for Gastric Cancer

Year:

2014

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

A Stampa

Referee:

Sì

Name of journal:

ANNALS OF SURGICAL ONCOLOGY

ISSN of journal:

1068-9265

N° Volume:

21

Number or Folder:

6

Page numbers:

2005-2011

Keyword:

Radical gastrectomy, curative resection, prognostic factors, recurrence, Computed Tomography, carcinoma, surgery, survival

Short description of contents:

The Italian Research Group for Gastric Cancer supports the practice of follow-up after radical surgery for gastric cancer. This multicenter, retrospective study (1998-2009) included patients with T1-4N0-3M0 gastric cancer who had undergone D2 gastrectomy and lymphadenectomy, with at least 15 lymph nodes examined, and who had developed recurrent disease. Timing and site of recurrence were correlated to the actual scheduled follow-up timing and modalities. From eight centers, 814 patients with recurrent cancer and over 1,754 (46.4 %) patients undergoing gastrectomy were investigated (median follow-up 31 months). The most frequent sites of recurrence were local/regional lymph nodes (35.4 %), liver (24.3 %), peritoneum (30.3 %), lung (10.4 %) and intraluminal (7.5 %). Ninety-four percent of the recurrences were diagnosed within 2 years and 98 % within 3 years. Thoracoabdominal computed tomography (CT) scan and (18)F-fluoro-2-deoxy-d-glucose positron emission tomography (18-FDG-PET) detected more than 90 % of recurrences, abdominal ultrasound detected 70 % and tumor markers detected 40 %, while < 10 % were identified by physical examination, chest X-ray, and upper gastrointestinal endoscopy. Twenty-six percent of patients with recurrence were treated, but only 3.2 % were treated with potentially radical intent. Oncological follow-up after radical surgery for gastric cancer should be focused in the first 3 years, and based mainly on thoracoabdominal CT scan and 18-FDG-PET.

Product ID:

86708

Handle IRIS:

11562/911203

Deposited On:

April 12, 2015

Last Modified:

November 15, 2022

Bibliographic citation:

Baiocchi, Gl; Marrelli, D; Verlato, Giuseppe; Morgagni, P; Giacopuzzi, Simone; Coniglio, A; Marchet, A; Rosa, F; Giulii Capponi, M; Di Leo, A; Saragoni, L; Ansaloni, L; Pacelli, F; Nitti, D; D’Ugo, D; Roviello, F; Tiberio, G; Giulini, Sm; DE MANZONI, Giovanni, Follow-up after gastrectomy for cancer. An appraisal of the Italian Research Group for Gastric Cancer «ANNALS OF SURGICAL ONCOLOGY» , vol. 21 , n. 6 , 2014 , pp. 2005-2011

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