Regulation of IL-8 gene expression in gliomas by microRNA miR-93
Year:
2015
Type of item:
Articolo in Rivista
Tipologia ANVUR:
Articolo su rivista
Language:
Inglese
Format:
Elettronico
Referee:
No
Name of journal:
BMC CANCER
ISSN of journal:
1471-2407
N° Volume:
15
Number or Folder:
1
Page numbers:
661-661
Keyword:
gliomas , chemokine Interleukin-8 (IL-8), miR-93
Short description of contents:
Different strategies have been proposed to target neoangiogenesis in gliomas, besides those targeting Vascular Endothelial Growth Factor (VEGF). The chemokine Interleukin-8 (IL-8) has been shown to possess both tumorigenic and proangiogenic properties. Although different pathways of induction of IL-8 gene expression have been already elucidated, few data are available on its post-transcriptional regulation in gliomas.