Publications

Authors:

Gigliotti, Carmen R.; Altabella, Luisa; Boschi, Federico; Crippa, Massimo; Spinelli, Antonello E.

Title:

In vivo and in vitro imaging using a multimodal optical system

Year:

2015

Type of item:

Contributo in atti di convegno

Tipologia ANVUR:

Contributo in Atti di convegno

Language:

Inglese

Format:

Elettronico

Congresso:

2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)

Place:

San Diego, CA

Period:

Oct. 31 2015-Nov. 7 2015

Page numbers:

1-3

Keyword:

in vivo imaging,in vitro imaging, super resolution

Short description of contents:

Bioluminescence in vitro studies are usually performed with dedicated microscopes. In this work, we proposed a novel image recovery algorithm and a multimodal system prototype to perform bioluminescence microscopy. A super resolution regularization algorithm (SRRA) was developed and applied in a feasibility study using Geant4 Monte Carlo (MC) simulation. The method was also tested using in vitro cells acquisition performed with the prototype. The results obtained with MC simulations showed an improvement in the spatial localization resolution from 90 μm to 10 μm. The processing of the in vitro mesothelioma cells image shows shrink of the localization full width half maximum (FWHM) from 110 μm to 13 μm. © 2015 IEEE.

Web page:

http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=7582161&isnumber=7581238

Product ID:

98419

Handle IRIS:

11562/966310

Last Modified:

March 28, 2023

Bibliographic citation:

Gigliotti, Carmen R.; Altabella, Luisa; Boschi, Federico; Crippa, Massimo; Spinelli, Antonello E., In vivo and in vitro imaging using a multimodal optical system  in Proceedings of 2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) , Proceedings of "2015 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)" , San Diego, CA , Oct. 31 2015-Nov. 7 2015 , 2015 , pp. 1-3

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