Publications

Authors:

DEL CURATOLO, Anais; Conciatori, Fabiana; Cesta Incani, Ursula; Bazzichetto, Chiara; Falcone, Italia; Corbo, Vincenzo; D'Agosto, Sabrina; Eramo, Adriana; Sette, Giovanni; Sperduti, Isabella; De Luca, Teresa; Marabese, Mirko; Shirasawa, Senji; De Maria, Ruggero; Scarpa, Aldo; Broggini, Massimo; Del Bufalo, Donatella; Cognetti, Francesco; Milella, Michele; Ciuffreda, Ludovica

Title:

Therapeutic potential of combined BRAF/MEK blockade in BRAF-wild type preclinical tumor models

Year:

2018

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

Elettronico

Referee:

No

Name of journal:

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

ISSN of journal:

1756-9966

N° Volume:

37

Number or Folder:

1

Page numbers:

140-140

Keyword:

BRAF; Combination therapy; MAPK; MEK; Paradoxical effect

Short description of contents:

Mounting evidence suggests that RAF-mediated MEK activation plays a crucial role in paradox MAPK (re)activation, leading to resistance and therapeutic failure with agents hitting a single step along the MAPK cascade.

Product ID:

103734

Handle IRIS:

11562/983403

Last Modified:

November 12, 2022

Bibliographic citation:

DEL CURATOLO, Anais; Conciatori, Fabiana; Cesta Incani, Ursula; Bazzichetto, Chiara; Falcone, Italia; Corbo, Vincenzo; D'Agosto, Sabrina; Eramo, Adriana; Sette, Giovanni; Sperduti, Isabella; De Luca, Teresa; Marabese, Mirko; Shirasawa, Senji; De Maria, Ruggero; Scarpa, Aldo; Broggini, Massimo; Del Bufalo, Donatella; Cognetti, Francesco; Milella, Michele; Ciuffreda, Ludovica, Therapeutic potential of combined BRAF/MEK blockade in BRAF-wild type preclinical tumor models «JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH» , vol. 37 , n. 1 , 2018 , pp. 140-140

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo