Pubblicazioni

Autori:

Barbieri, Giulia; Cazzoletti, Lucia; Melotti, Roberto; Hantikainen, Essi; Lundin, Rebecca; Barin, Laura; Gögele, Martin; Riegler, Peter; Ferraro, Pietro Manuel; Pramstaller, Peter Paul; Gambaro, Giovanni; Zanolin, Maria Elisabetta; Pattaro, Cristian

Titolo:

Development and evaluation of a kidney health questionnaire and estimates of chronic kidney disease prevalence in the Cooperative Health Research in South Tyrol (CHRIS) study

Anno:

2024

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Referee:

No

Nome rivista:

JN. JOURNAL OF NEPHROLOGY

ISSN Rivista:

1724-6059

N° Volume:

38

Numero o Fascicolo:

2

Intervallo pagine:

521-530

Parole chiave:

Awareness; CKD; Chronic kidney disease; Cooperative Health Research in South Tyrol (CHRIS) study; Prevalence; Questionnaire

Breve descrizione dei contenuti:

Background: Kidney diseases are a public health burden but are poorly investigated in the general population. In light of inadequate survey tools, we developed a novel questionnaire for use in population-based studies, to retrospectively assess kidney diseases. Methods: The questionnaire covered general kidney diseases, reduced kidney function, and renal surgeries. It was administered between 2011 and 2018 to 11,684 participants (median age = 45 years) of the Cooperative Health Research in South Tyrol (CHRIS) study. Fasting estimated glomerular filtration rate (eGFR) and urinary albumin-to-creatinine ratio (UACR) were measured. By factor analysis we contextualized the questionnaire content with respect to the biochemical measurements. We estimated overall and sex-stratified prevalence of kidney diseases, including possible CKD, calibrating them to the general target population via relative sampling weights. Results: Population-representative prevalence of glomerulonephritis, pyelonephritis, and congenital kidney diseases was 1.0%, 3.0%, and 0.2%, respectively, with corresponding odds ratios for females versus males of 1.4 (95% confidence interval: 1.0, 2.0), 8.7 (6.2, 12.3), and 0.7 (0.3, 1.6), respectively. Prevalence of kidney dysfunction (eGFR < 60 mL/min/1.73 m2 or UACR > 30 mg/g) was 8.59%, while prevalence of self-reported CKD was 0.69%, indicating 95.3% of lack of disease awareness, with a similar figure in people with diabetes or hypertension. Overall, 15.76% of the population was affected by a kidney disease of any kind. Conclusion: In the Val Venosta/Vinschgau alpine district, CKD prevalence aligned with Western European estimates. Kidney health questionnaire implementation in population studies is feasible and valuable to assess CKD awareness, which we found to be dramatically low.

Note:

Maria Elisabetta Zanolin and Cristian Pattaro Jointly supervised the work. Epub 2024 Nov 27

Id prodotto:

142895

Handle IRIS:

11562/1146228

ultima modifica:

5 aprile 2025

Citazione bibliografica:

Barbieri, Giulia; Cazzoletti, Lucia; Melotti, Roberto; Hantikainen, Essi; Lundin, Rebecca; Barin, Laura; Gögele, Martin; Riegler, Peter; Ferraro, Pietro Manuel; Pramstaller, Peter Paul; Gambaro, Giovanni; Zanolin, Maria Elisabetta; Pattaro, Cristian, Development and evaluation of a kidney health questionnaire and estimates of chronic kidney disease prevalence in the Cooperative Health Research in South Tyrol (CHRIS) study «JN. JOURNAL OF NEPHROLOGY» , vol. 38 , n. 2 , 2024 , pp. 521-530

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