- Autori:
-
Corianò, Matilde; Lazzarin, Alessandro; Maffezzoli, Michele; Santoni, Matteo; Mazzaschi, Giulia; Rodella, Sara; Simoni, Nicola; Lai, Eleonora; Maruzzo, Marco; Basso, Umberto; Bimbatti, Davide; Iacovelli, Roberto; Anghelone, Annunziato; Fiala, Ondřej; Rebuzzi, Sara Elena; Fornarini, Giuseppe; Lolli, Cristian; Massari, Francesco; Rosellini, Matteo; Mollica, Veronica; Nasso, Cecilia; Acunzo, Alessandro; Silini, Enrico Maria; Quaini, Federico; De Filippo, Massimo; Brunelli, Matteo; Banna, Giuseppe L; Rescigno, Pasquale; Signori, Alessio; Buti, Sebastiano
- Titolo:
-
Role of Hb to RDW ratio in metastatic renal cell carcinoma patients treated with first-line immunotherapy combinations
- Anno:
-
2025
- Tipologia prodotto:
-
Articolo in Rivista
- Tipologia ANVUR:
- Articolo su rivista
- Lingua:
-
Inglese
- Referee:
-
No
- Nome rivista:
- IMMUNOTHERAPY
- ISSN Rivista:
- 1750-743X
- N° Volume:
-
17
- Numero o Fascicolo:
-
1
- Intervallo pagine:
-
25-35
- Parole chiave:
-
NLR; Prognostic score; RDW; hemoglobin; immune checkpoint inhibitors; metastatic renal cell carcinoma; ratio; tyrosine-kinase inhibitors
- Breve descrizione dei contenuti:
- Background: The present study aimed to investigate the prognostic and predictive roles of Hb/RDW ratio in patients with mRCC treated with first-line immunotherapy combinations (TKI plus ICI or ICI plus ICI). Materials and methods: We performed a sub-analysis of a multicenter retrospective observational study (ARON-1 project) involving patients with mRCC treated with first-line immunotherapy combinations. Results: Three hundred and twenty-nine patients were enrolled, 244 males and 85 females. Median age was 65.5 years. The prognostic impact of the Hb/RDW ratio on PFS and OS was observed in the whole population examined. Hb/RDW ratio had a correlation with neutrophil-to-lymphocyte ratio (NLR), a blood inflammatory parameter. Conclusion: Hb/RDW ratio is a new inflammatory prognostic factor, easy to use in daily clinical practice.
- Note:
- Epub 2025 Jan 20
- Id prodotto:
-
143947
- Handle IRIS:
-
11562/1151107
- ultima modifica:
-
4 aprile 2025
- Citazione bibliografica:
-
Corianò, Matilde; Lazzarin, Alessandro; Maffezzoli, Michele; Santoni, Matteo; Mazzaschi, Giulia; Rodella, Sara; Simoni, Nicola; Lai, Eleonora; Maruzzo, Marco; Basso, Umberto; Bimbatti, Davide; Iacovelli, Roberto; Anghelone, Annunziato; Fiala, Ondřej; Rebuzzi, Sara Elena; Fornarini, Giuseppe; Lolli, Cristian; Massari, Francesco; Rosellini, Matteo; Mollica, Veronica; Nasso, Cecilia; Acunzo, Alessandro; Silini, Enrico Maria; Quaini, Federico; De Filippo, Massimo; Brunelli, Matteo; Banna, Giuseppe L; Rescigno, Pasquale; Signori, Alessio; Buti, Sebastiano,
Role of Hb to RDW ratio in metastatic renal cell carcinoma patients treated with first-line immunotherapy combinations
«IMMUNOTHERAPY»
, vol.
17
, n.
1
,
2025
,
pp. 25-35
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