Pubblicazioni

Autori:

De Robertis, Riccardo; Capelli, Paola; Longo, Chiara; D'Onofrio, Mirko

Titolo:

Ductal Adenocarcinoma: Downstaging

Anno:

2022

Tipologia prodotto:

Contributo in volume (Capitolo o Saggio)

Tipologia ANVUR:

Contributo in volume (Capitolo o Saggio)

Lingua:

Inglese

Titolo libro:

Imaging and Pathology of Pancreatic Neoplasms A Pictorial Atlas

Casa editrice:

Springer

ISBN:

9783031098314

Intervallo pagine:

99-139

Parole chiave:

CT; Downstaging; MRI; Pancreatic adenocarcinoma; Pancreatic cancer; Pathologic correlations

Breve descrizione dei contenuti:

Pancreatic ductal adenocarcinoma (PDAC) is usually diagnosed at an advanced stage of disease with involvement of major peripancreatic vessels, extra-pancreatic invasion, or metastases. For this reason, fewer than 20% of patients are suitable for surgical resection (Laeseke et al., Radiology 277:644–661, 2015). An increasing number of unresectable PDACs undergo surgery after neoadjuvant therapy. Unresectable PDAC patients, including locally advanced and borderline resectable cancers, can be downstaged by neoadjuvant chemoradiotherapy. Resectability of PDAC is a multidisciplinary concept, and imaging has a central role for the proper description of the extent of tumor. High-quality imaging of the pancreas should be performed at presentation and following neoadjuvant treatments to provide adequate staging and assessment of resectability status. Restaging after chemotherapy is always more problematic with a lower accuracy by using imaging modalities to correctly assess therapeutic responses and downstaging.

Id prodotto:

146183

Handle IRIS:

11562/1163937

ultima modifica:

6 giugno 2025

Citazione bibliografica:

De Robertis, Riccardo; Capelli, Paola; Longo, Chiara; D'Onofrio, Mirko, Ductal Adenocarcinoma: Downstaging Imaging and Pathology of Pancreatic Neoplasms A Pictorial Atlas , Springer , 2022 , pp. 99-139

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